Supplementary data for "synthesis and biological evaluation of highly potent fungicidal deoxy-hygrophorones"

Abstract: Based on naturally occurring hygrophorones, racemic di- and mono hydroxylated cyclopentenones bearing an aliphatic side chain have been produced in short synthetic sequences starting from furfuryl aldehyde. For the series of dihydroxylated trans-con-figured derivatives, an Ach¬matowicz and a Caddick-ring contrac¬tion were employed, and for the series of trans-configured mono-hydroxylated derivatives a Piancatelli-rearrange¬ment. All final products showed good to excellent fungicidal activities against the plant pathogens B. cinerea, S. tritici and P. infestans.