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{
            
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  "author": "Wei, Lei",
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  "author": "Wei, Lei",
            
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  "author_email": "",
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  "author_email": "",
            
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  "citation": [],
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  "citation": [],
            
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  "creator_user_id": "17755db4-395a-4b3b-ac09-e8e3484ca700",
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  "creator_user_id": "17755db4-395a-4b3b-ac09-e8e3484ca700",
            
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  "doi": "10.1594/PANGAEA.846883",
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  "doi": "10.1594/PANGAEA.846883",
            
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  "doi_date_published": "2015",
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  "doi_date_published": "2015",
            
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  "doi_publisher": "",
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  "doi_publisher": "",
            
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  "doi_status": "True",
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  "doi_status": "True",
            
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  "extra_authors": [
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  "extra_authors": [
            
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    {
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    {
            
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      "extra_author": "Wang, Qing",
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      "extra_author": "Wang, Qing",
            
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      "familyName": "Wang",
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      "familyName": "Wang",
            
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      "givenName": "Qing",
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      "givenName": "Qing",
            
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      "orcid": ""
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      "orcid": ""
            
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    },
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    },
            
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    {
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    {
            
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      "extra_author": "Ning, Xuanxuan",
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      "extra_author": "Ning, Xuanxuan",
            
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      "familyName": "Ning",
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      "familyName": "Ning",
            
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      "givenName": "Xuanxuan",
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      "givenName": "Xuanxuan",
            
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      "orcid": ""
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      "orcid": ""
            
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    },
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    },
            
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    {
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    {
            
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      "extra_author": "Mu, Changkao",
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      "extra_author": "Mu, Changkao",
            
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      "familyName": "Mu",
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      "familyName": "Mu",
            
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      "givenName": "Changkao",
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      "givenName": "Changkao",
            
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      "orcid": ""
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      "orcid": ""
            
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    },
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    },
            
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    {
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    {
            
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      "extra_author": "Wang, Chunlin",
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      "extra_author": "Wang, Chunlin",
            
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      "familyName": "Wang",
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      "familyName": "Wang",
            
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      "givenName": "Chunlin",
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      "givenName": "Chunlin",
            
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      "orcid": ""
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      "orcid": ""
            
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    },
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    },
            
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    {
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    {
            
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      "extra_author": "Cao, Ruiwen",
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      "extra_author": "Cao, Ruiwen",
            
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      "familyName": "Cao",
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      "familyName": "Cao",
            
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      "givenName": "Ruiwen",
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      "givenName": "Ruiwen",
            
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      "orcid": "0000-0001-7274-7988"
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      "orcid": "0000-0001-7274-7988"
            
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    },
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    },
            
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    {
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    {
            
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      "extra_author": "Wu, Huifeng",
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      "extra_author": "Wu, Huifeng",
            
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      "familyName": "Wu",
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      "familyName": "Wu",
            
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      "givenName": "Huifeng",
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      "givenName": "Huifeng",
            
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      "orcid": ""
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      "orcid": ""
            
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    },
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    },
            
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    {
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    {
            
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      "extra_author": "Cong, Ming",
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      "extra_author": "Cong, Ming",
            
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      "familyName": "Cong",
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      "familyName": "Cong",
            
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      "givenName": "Ming",
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      "givenName": "Ming",
            
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      "orcid": ""
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      "orcid": ""
            
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    },
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    },
            
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    {
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    {
            
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      "extra_author": "Li, Fei",
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      "extra_author": "Li, Fei",
            
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      "familyName": "Li",
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      "familyName": "Li",
            
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      "givenName": "Fei",
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      "givenName": "Fei",
            
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      "orcid": "0000-0002-9718-6627"
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      "orcid": "0000-0002-9718-6627"
            
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    },
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    },
            
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    {
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    {
            
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      "extra_author": "Ji, Chenglong",
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      "extra_author": "Ji, Chenglong",
            
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      "familyName": "Ji",
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      "familyName": "Ji",
            
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      "givenName": "Chenglong",
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      "givenName": "Chenglong",
            
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      "orcid": ""
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      "orcid": ""
            
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    },
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    },
            
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    {
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    {
            
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      "extra_author": "Zhao, Jianmin",
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      "extra_author": "Zhao, Jianmin",
            
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      "familyName": "Zhao",
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      "familyName": "Zhao",
            
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      "givenName": "Jianmin",
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      "givenName": "Jianmin",
            
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      "orcid": ""
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      "orcid": ""
            
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    }
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    }
            
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  ],
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  ],
            
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  "familyName": "Wei",
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  "familyName": "Wei",
            
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  "givenName": "Lei",
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  "givenName": "Lei",
            
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  "groups": [],
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  "groups": [],
            
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  "id": "bf11a198-688d-42de-a939-bd616c593af3",
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  "isopen": false,
            
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  "license_id": "CC-BY-3.0",
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  "license_id": "CC-BY-3.0",
            
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  "license_title": "CC-BY-3.0",
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  "license_title": "CC-BY-3.0",
            
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  "metadata_created": "2024-11-29T11:45:24.181489",
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  "metadata_created": "2024-11-29T11:45:24.181489",
            
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  "metadata_modified": "2024-11-29T11:45:24.181495",
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  "metadata_modified": "2024-11-30T14:30:25.218791",
            
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  "name": "png-doi-10-1594-pangaea-846883",
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  "name": "png-doi-10-1594-pangaea-846883",
            
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  "notes": "Ocean acidification (OA) has been found to affect an array 
82
  "notes": "Ocean acidification (OA) has been found to affect an array 
            
83
of normal physiological processes in mollusks, especially posing a 
83
of normal physiological processes in mollusks, especially posing a 
            
84
significant threat to the fabrication process of mollusk shell. In the 
84
significant threat to the fabrication process of mollusk shell. In the 
            
85
current study, the impact of exposure to elevated pCO2 condition was 
85
current study, the impact of exposure to elevated pCO2 condition was 
            
86
investigated in mantle tissue of Crassostrea gigas by an integrated 
86
investigated in mantle tissue of Crassostrea gigas by an integrated 
            
87
metabolomic and proteomic approach. Analysis of metabolome and 
87
metabolomic and proteomic approach. Analysis of metabolome and 
            
88
proteome revealed that elevated pCO2 could affect energy metabolism in 
88
proteome revealed that elevated pCO2 could affect energy metabolism in 
            
89
oyster C. gigas, marked by differentially altered ATP, succinate, MDH, 
89
oyster C. gigas, marked by differentially altered ATP, succinate, MDH, 
            
90
PEPCK and ALDH levels. Moreover, the up-regulated calponin-2, 
90
PEPCK and ALDH levels. Moreover, the up-regulated calponin-2, 
            
91
tropomyosins and myosin light chains indicated that elevated pCO2 
91
tropomyosins and myosin light chains indicated that elevated pCO2 
            
92
probably caused disturbances in cytoskeleton structure in mantle 
92
probably caused disturbances in cytoskeleton structure in mantle 
            
93
tissue of oyster C. gigas. This work demonstrated that a combination 
93
tissue of oyster C. gigas. This work demonstrated that a combination 
            
94
of proteomics and metabolomics could provide important insights into 
94
of proteomics and metabolomics could provide important insights into 
            
95
the effects of OA at molecular levels.",
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the effects of OA at molecular levels.",
            
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    "approval_status": "approved",
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    "approval_status": "approved",
            
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    "created": "2024-11-29T11:32:00.143130",
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    "description": "PANGAEA (Data Publisher for Earth & Environmental 
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Science): The information system PANGAEA is operated as an Open Access 
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Science): The information system PANGAEA is operated as an Open Access 
            
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library aimed at archiving, publishing and distributing georeferenced 
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library aimed at archiving, publishing and distributing georeferenced 
            
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data from earth system research. PANGAEA guarantees long-term 
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data from earth system research. PANGAEA guarantees long-term 
            
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availability (greater than 10 years) of its content. PANGAEA is open 
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availability (greater than 10 years) of its content. PANGAEA is open 
            
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to any project, institution, or individual scientist to use or to 
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to any project, institution, or individual scientist to use or to 
            
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archive and publish data. PANGAEA focuses on georeferenced 
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archive and publish data. PANGAEA focuses on georeferenced 
            
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observational data, experimental data, and models/simulations. 
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observational data, experimental data, and models/simulations. 
            
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Citability, comprehensive metadata descriptions, interoperability of 
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Citability, comprehensive metadata descriptions, interoperability of 
            
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data and metadata, a high degree of structural and semantic 
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data and metadata, a high degree of structural and semantic 
            
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harmonization of the data inventory as well as the commitment of the 
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harmonization of the data inventory as well as the commitment of the 
            
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hosting institutions ensures FAIRness of archived data.",
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hosting institutions ensures FAIRness of archived data.",
            
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    "is_organization": true,
            
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    "name": "pangaea_biosphere",
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    "name": "pangaea_biologicalclassification",
            
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    "state": "active",
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    "state": "active",
            
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    "title": "PANGAEA (Biosphere)",
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    "title": "PANGAEA (Biological Classification)",
            
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    "type": "organization"
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    "type": "organization"
            
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  "private": false,
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  "private": false,
            
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  "publication_year": "2015",
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  "publication_year": "2015",
            
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  "related_identifiers": [
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  "related_identifiers": [
            
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    {
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    {
            
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      "authors": "Wei Lei,Wang Qing,Ning Xuanxuan,Mu Changkao,Wang 
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      "authors": "Wei Lei,Wang Qing,Ning Xuanxuan,Mu Changkao,Wang 
            
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Chunlin,Cao Ruiwen,Wu Huifeng,Cong Ming,Li Fei,Ji Chenglong,Zhao 
128
Chunlin,Cao Ruiwen,Wu Huifeng,Cong Ming,Li Fei,Ji Chenglong,Zhao 
            
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Jianmin",
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Jianmin",
            
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      "email_authors": 
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      "email_authors": 
            
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cao@qlu.edu.cn,hfwu@yic.ac.cn,,feinan.li@gmail.com,,jmzhao@yic.ac.cn",
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cao@qlu.edu.cn,hfwu@yic.ac.cn,,feinan.li@gmail.com,,jmzhao@yic.ac.cn",
            
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      "identifier": "https://doi.org/10.1016/j.cbd.2014.12.001",
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      "identifier": "https://doi.org/10.1016/j.cbd.2014.12.001",
            
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      "identifier_type": "DOI",
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      "identifier_type": "DOI",
            
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      "orcid_authors": 
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      "orcid_authors": 
            
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",,,,,0000-0001-7274-7988,,,0000-0002-9718-6627,,",
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",,,,,0000-0001-7274-7988,,,0000-0002-9718-6627,,",
            
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      "relation_type": "IsSupplementTo",
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      "relation_type": "IsSupplementTo",
            
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      "source": "Comparative Biochemistry and Physiology Part D: 
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      "source": "Comparative Biochemistry and Physiology Part D: 
            
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Genomics & Proteomics",
138
Genomics & Proteomics",
            
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      "title": "Combined metabolome and proteome analysis of the 
139
      "title": "Combined metabolome and proteome analysis of the 
            
140
mantle tissue from Pacific oyster Crassostrea gigas exposed to 
140
mantle tissue from Pacific oyster Crassostrea gigas exposed to 
            
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elevated pCO2",
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elevated pCO2",
            
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      "year": "2015"
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      "year": "2015"
            
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    },
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    },
            
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    {
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    {
            
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      "authors": "Gattuso Jean-Pierre,Epitalon Jean-Marie,Lavigne 
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      "authors": "Gattuso Jean-Pierre,Epitalon Jean-Marie,Lavigne 
            
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H\u00e9lo\u00efse",
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H\u00e9lo\u00efse",
            
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      "email_authors": 
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      "email_authors": 
            
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"jean-pierre.gattuso@imev-mer.fr,,hlavigne@naturalsciences.be",
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"jean-pierre.gattuso@imev-mer.fr,,hlavigne@naturalsciences.be",
            
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      "identifier": "https://cran.r-project.org/package=seacarb",
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      "identifier": "https://cran.r-project.org/package=seacarb",
            
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      "identifier_type": "DOI",
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      "identifier_type": "DOI",
            
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      "orcid_authors": "0000-0002-4533-4114,,",
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      "orcid_authors": "0000-0002-4533-4114,,",
            
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      "relation_type": "References",
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      "relation_type": "References",
            
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      "source": "",
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      "source": "",
            
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      "title": "seacarb: seawater carbonate chemistry with R. R 
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      "title": "seacarb: seawater carbonate chemistry with R. R 
            
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package version 3.0.6",
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package version 3.0.6",
            
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      "year": "2015"
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      "year": "2015"
            
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    }
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    }
            
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  ],
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  "repository_name": "PANGAEA (Data Publisher for Earth & 
            
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Environmental Science)",
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Environmental Science)",
            
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  "resource_type": "text/tab-separated-values - filename: Wei_2015",
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  "resources": [],
            
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  "source_metadata_created": "2015",
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  "source_metadata_created": "2015",
            
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  "state": "active",
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  "state": "active",
            
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    {
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    {
            
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      "subject_area_additional": "",
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      "subject_area_additional": "",
            
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      "subject_area_name": "BiologicalClassification"
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      "subject_area_name": "BiologicalClassification"
            
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    },
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    },
            
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    {
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    {
            
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      "subject_area_additional": "",
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      "subject_area_additional": "",
            
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      "subject_area_name": "Biosphere"
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      "subject_area_name": "Biosphere"
            
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    },
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    },
            
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    {
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    {
            
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      "subject_area_additional": "",
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      "subject_area_additional": "",
            
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      "subject_area_name": "Chemistry"
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      "subject_area_name": "Chemistry"
            
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    }
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    }
            
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  ],
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  ],
            
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  "tags": [
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  "tags": [
            
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    {
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    {
            
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      "display_name": "1000 L or  1 m2",
            
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      "id": "d920ecdb-c44e-43f2-bb4c-ffdc3a3c398c",
            
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      "name": "1000 L or  1 m2",
            
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    },
            
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    {
            
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      "display_name": "Animalia",
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      "display_name": "Animalia",
            
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      "id": "e645e194-a2f7-40f1-ae7c-c1496be6f6bf",
            
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      "name": "Animalia",
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      "name": "Animalia",
            
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      "state": "active",
            
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    },
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    },
            
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    {
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    {
            
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      "display_name": "Benthic animals",
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      "display_name": "Benthic animals",
            
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      "name": "Benthic animals",
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      "name": "Benthic animals",
            
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      "display_name": "Benthos",
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      "display_name": "Benthos",
            
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      "id": "55bc70f2-ff73-4d9a-89f6-16358d0d9b87",
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      "id": "55bc70f2-ff73-4d9a-89f6-16358d0d9b87",
            
200
      "name": "Benthos",
207
      "name": "Benthos",
            
201
      "state": "active",
208
      "state": "active",
            
202
      "vocabulary_id": null
209
      "vocabulary_id": null
            
203
    },
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    },
            
204
    {
211
    {
            
205
      "display_name": "Coast and continental shelf",
212
      "display_name": "Coast and continental shelf",
            
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      "id": "58eb1929-34b5-4fd9-ac44-824f0e51de40",
213
      "id": "58eb1929-34b5-4fd9-ac44-824f0e51de40",
            
207
      "name": "Coast and continental shelf",
214
      "name": "Coast and continental shelf",
            
208
      "state": "active",
215
      "state": "active",
            
209
      "vocabulary_id": null
216
      "vocabulary_id": null
            
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    },
217
    },
            
211
    {
218
    {
            
t
212
      "display_name": "Containers and aquaria 20-1000 L or  1 m2",
t
219
      "display_name": "Containers and aquaria 20",
            
213
      "id": "a9d9036d-3fe8-4fb1-bcb9-07b8a3a3fe11",
220
      "id": "18d57eca-7aec-4d8a-9a57-92bf32a45d53",
            
214
      "name": "Containers and aquaria 20-1000 L or  1 m2",
221
      "name": "Containers and aquaria 20",
            
215
      "state": "active",
222
      "state": "active",
            
216
      "vocabulary_id": null
223
      "vocabulary_id": null
            
217
    },
224
    },
            
218
    {
225
    {
            
219
      "display_name": "Crassostrea gigas",
226
      "display_name": "Crassostrea gigas",
            
220
      "id": "44a90705-8dc8-41ad-a3c4-d60cdbce94bf",
227
      "id": "44a90705-8dc8-41ad-a3c4-d60cdbce94bf",
            
221
      "name": "Crassostrea gigas",
228
      "name": "Crassostrea gigas",
            
222
      "state": "active",
229
      "state": "active",
            
223
      "vocabulary_id": null
230
      "vocabulary_id": null
            
224
    },
231
    },
            
225
    {
232
    {
            
226
      "display_name": "Gene expression incl. proteomics",
233
      "display_name": "Gene expression incl. proteomics",
            
227
      "id": "a266e76f-1f2a-427a-97e6-8e248d591f17",
234
      "id": "a266e76f-1f2a-427a-97e6-8e248d591f17",
            
228
      "name": "Gene expression incl. proteomics",
235
      "name": "Gene expression incl. proteomics",
            
229
      "state": "active",
236
      "state": "active",
            
230
      "vocabulary_id": null
237
      "vocabulary_id": null
            
231
    },
238
    },
            
232
    {
239
    {
            
233
      "display_name": "Laboratory experiment",
240
      "display_name": "Laboratory experiment",
            
234
      "id": "c6c00754-c769-4932-a517-bff2c9512884",
241
      "id": "c6c00754-c769-4932-a517-bff2c9512884",
            
235
      "name": "Laboratory experiment",
242
      "name": "Laboratory experiment",
            
236
      "state": "active",
243
      "state": "active",
            
237
      "vocabulary_id": null
244
      "vocabulary_id": null
            
238
    },
245
    },
            
239
    {
246
    {
            
240
      "display_name": "Mollusca",
247
      "display_name": "Mollusca",
            
241
      "id": "006d5f6d-11b3-4c34-a35a-879d7cd074c8",
248
      "id": "006d5f6d-11b3-4c34-a35a-879d7cd074c8",
            
242
      "name": "Mollusca",
249
      "name": "Mollusca",
            
243
      "state": "active",
250
      "state": "active",
            
244
      "vocabulary_id": null
251
      "vocabulary_id": null
            
245
    },
252
    },
            
246
    {
253
    {
            
247
      "display_name": "Single species",
254
      "display_name": "Single species",
            
248
      "id": "88de69be-3bdd-4cf8-b6a1-386d72c5888d",
255
      "id": "88de69be-3bdd-4cf8-b6a1-386d72c5888d",
            
249
      "name": "Single species",
256
      "name": "Single species",
            
250
      "state": "active",
257
      "state": "active",
            
251
      "vocabulary_id": null
258
      "vocabulary_id": null
            
252
    },
259
    },
            
253
    {
260
    {
            
254
      "display_name": "South Pacific",
261
      "display_name": "South Pacific",
            
255
      "id": "d9590299-7cec-4210-a3e5-eff66f886e09",
262
      "id": "d9590299-7cec-4210-a3e5-eff66f886e09",
            
256
      "name": "South Pacific",
263
      "name": "South Pacific",
            
257
      "state": "active",
264
      "state": "active",
            
258
      "vocabulary_id": null
265
      "vocabulary_id": null
            
259
    },
266
    },
            
260
    {
267
    {
            
261
      "display_name": "Temperate",
268
      "display_name": "Temperate",
            
262
      "id": "31aaeb0c-a4a5-4a8e-9c90-be1eff0cac91",
269
      "id": "31aaeb0c-a4a5-4a8e-9c90-be1eff0cac91",
            
263
      "name": "Temperate",
270
      "name": "Temperate",
            
264
      "state": "active",
271
      "state": "active",
            
265
      "vocabulary_id": null
272
      "vocabulary_id": null
            
266
    }
273
    }
            
267
  ],
274
  ],
            
268
  "title": "Combined metabolome and proteome analysis of the mantle 
275
  "title": "Combined metabolome and proteome analysis of the mantle 
            
269
tissue from Pacific oyster Crassostrea gigas exposed to elevated 
276
tissue from Pacific oyster Crassostrea gigas exposed to elevated 
            
270
pCO2",
277
pCO2",
            
271
  "type": "vdataset",
278
  "type": "vdataset",
            
272
  "url": "https://doi.org/10.1594/PANGAEA.846883"
279
  "url": "https://doi.org/10.1594/PANGAEA.846883"
            
273
}
280
}