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{
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{
            
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  "author": "Dineshram, R",
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  "author": "Dineshram, R",
            
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  "author_email": "",
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  "author_email": "",
            
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  "citation": [],
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  "citation": [],
            
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  "creator_user_id": "17755db4-395a-4b3b-ac09-e8e3484ca700",
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  "creator_user_id": "17755db4-395a-4b3b-ac09-e8e3484ca700",
            
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  "doi": "10.1594/PANGAEA.823757",
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  "doi": "10.1594/PANGAEA.823757",
            
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  "doi_date_published": "2012",
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  "doi_date_published": "2012",
            
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  "doi_publisher": "",
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  "doi_publisher": "",
            
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  "doi_status": "True",
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  "doi_status": "True",
            
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  "extra_authors": [
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  "extra_authors": [
            
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    {
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    {
            
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      "extra_author": "Wong, Kevin K W",
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      "extra_author": "Wong, Kevin K W",
            
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      "familyName": "Wong",
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      "familyName": "Wong",
            
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      "givenName": "Kevin K W",
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      "givenName": "Kevin K W",
            
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      "orcid": ""
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      "orcid": ""
            
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    },
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    },
            
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    {
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    {
            
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      "extra_author": "Shu, Xiao",
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      "extra_author": "Shu, Xiao",
            
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      "familyName": "Shu",
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      "familyName": "Shu",
            
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      "givenName": "Xiao",
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      "givenName": "Xiao",
            
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      "orcid": ""
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      "orcid": ""
            
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    },
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    },
            
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    {
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    {
            
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      "extra_author": "Yu, Ziniu",
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      "extra_author": "Yu, Ziniu",
            
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      "familyName": "Yu",
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      "familyName": "Yu",
            
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      "givenName": "Ziniu",
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      "givenName": "Ziniu",
            
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      "orcid": ""
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      "orcid": ""
            
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    },
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    },
            
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    {
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    {
            
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      "extra_author": "Qian, Pei Yuan",
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      "extra_author": "Qian, Pei Yuan",
            
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      "familyName": "Qian",
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      "familyName": "Qian",
            
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      "givenName": "Pei Yuan",
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      "givenName": "Pei Yuan",
            
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      "orcid": "0000-0003-4074-9078"
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      "orcid": "0000-0003-4074-9078"
            
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    },
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    },
            
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    {
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    {
            
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      "extra_author": "Thiyagarajan, Vengatesen",
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      "extra_author": "Thiyagarajan, Vengatesen",
            
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      "familyName": "Thiyagarajan",
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      "familyName": "Thiyagarajan",
            
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      "givenName": "Vengatesen",
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      "givenName": "Vengatesen",
            
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      "orcid": "0000-0002-2062-4799"
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      "orcid": "0000-0002-2062-4799"
            
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    }
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    }
            
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  ],
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  ],
            
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  "familyName": "Dineshram",
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  "familyName": "Dineshram",
            
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  "givenName": "R",
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  "givenName": "R",
            
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  "groups": [],
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  "groups": [],
            
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  "id": "62b5316d-76ae-43c0-b0ed-3c43b85c10f9",
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  "id": "62b5316d-76ae-43c0-b0ed-3c43b85c10f9",
            
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  "isopen": false,
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  "isopen": false,
            
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  "license_id": "CC-BY-3.0",
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  "license_id": "CC-BY-3.0",
            
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  "license_title": "CC-BY-3.0",
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  "license_title": "CC-BY-3.0",
            
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  "metadata_created": "2024-11-29T11:34:45.563893",
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  "metadata_created": "2024-11-29T11:34:45.563893",
            
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  "metadata_modified": "2024-11-29T11:34:45.563900",
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  "metadata_modified": "2024-11-30T10:41:09.215179",
            
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  "name": "png-doi-10-1594-pangaea-823757",
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  "name": "png-doi-10-1594-pangaea-823757",
            
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  "notes": "Most calcifying organisms show depressed metabolic, growth 
52
  "notes": "Most calcifying organisms show depressed metabolic, growth 
            
53
and calcification rates as symptoms to high-CO(2) due to ocean 
53
and calcification rates as symptoms to high-CO(2) due to ocean 
            
54
acidification (OA) process. Analysis of the global expression pattern 
54
acidification (OA) process. Analysis of the global expression pattern 
            
55
of proteins (proteome analysis) represents a powerful tool to examine 
55
of proteins (proteome analysis) represents a powerful tool to examine 
            
56
these physiological symptoms at molecular level, but its applications 
56
these physiological symptoms at molecular level, but its applications 
            
57
are inadequate. To address this knowledge gap, 2-DE coupled with mass 
57
are inadequate. To address this knowledge gap, 2-DE coupled with mass 
            
58
spectrophotometer was used to compare the global protein expression 
58
spectrophotometer was used to compare the global protein expression 
            
59
pattern of oyster larvae exposed to ambient and to high-CO(2). 
59
pattern of oyster larvae exposed to ambient and to high-CO(2). 
            
60
Exposure to OA resulted in marked reduction of global protein 
60
Exposure to OA resulted in marked reduction of global protein 
            
61
expression with a decrease or loss of 71 proteins (18% of the 
61
expression with a decrease or loss of 71 proteins (18% of the 
            
62
expressed proteins in control), indicating a wide-spread depression of 
62
expressed proteins in control), indicating a wide-spread depression of 
            
63
metabolic genes expression in larvae reared under OA. This is, to our 
63
metabolic genes expression in larvae reared under OA. This is, to our 
            
64
knowledge, the first proteome analysis that provides insights into the 
64
knowledge, the first proteome analysis that provides insights into the 
            
65
link between physiological suppression and protein down-regulation 
65
link between physiological suppression and protein down-regulation 
            
66
under OA in oyster larvae.",
66
under OA in oyster larvae.",
            
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  "num_resources": 0,
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  "num_resources": 0,
            
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  "num_tags": 13,
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  "orcid": "",
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  "orcid": "",
            
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  "organization": {
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  "organization": {
            
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    "approval_status": "approved",
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    "approval_status": "approved",
            
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    "created": "2024-11-29T11:32:00.143130",
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    "created": "2024-11-30T10:25:26.439072",
            
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    "description": "PANGAEA (Data Publisher for Earth & Environmental 
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    "description": "PANGAEA (Data Publisher for Earth & Environmental 
            
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Science): The information system PANGAEA is operated as an Open Access 
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Science): The information system PANGAEA is operated as an Open Access 
            
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library aimed at archiving, publishing and distributing georeferenced 
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library aimed at archiving, publishing and distributing georeferenced 
            
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data from earth system research. PANGAEA guarantees long-term 
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data from earth system research. PANGAEA guarantees long-term 
            
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availability (greater than 10 years) of its content. PANGAEA is open 
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availability (greater than 10 years) of its content. PANGAEA is open 
            
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to any project, institution, or individual scientist to use or to 
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to any project, institution, or individual scientist to use or to 
            
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archive and publish data. PANGAEA focuses on georeferenced 
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archive and publish data. PANGAEA focuses on georeferenced 
            
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observational data, experimental data, and models/simulations. 
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observational data, experimental data, and models/simulations. 
            
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Citability, comprehensive metadata descriptions, interoperability of 
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Citability, comprehensive metadata descriptions, interoperability of 
            
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data and metadata, a high degree of structural and semantic 
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data and metadata, a high degree of structural and semantic 
            
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harmonization of the data inventory as well as the commitment of the 
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harmonization of the data inventory as well as the commitment of the 
            
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hosting institutions ensures FAIRness of archived data.",
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hosting institutions ensures FAIRness of archived data.",
            
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    "id": "3226ef9c-20d1-43fd-ba8f-fa35c8c9fb5d",
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    "id": "c2816fc6-b5ce-42c9-b5a4-11709b658b82",
            
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    "image_url": "pangaea_topicbiosphere.png",
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    "image_url": "pangaea_topicecology.png",
            
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    "is_organization": true,
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    "is_organization": true,
            
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    "name": "pangaea_biosphere",
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    "name": "pangaea_ecology",
            
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    "state": "active",
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    "state": "active",
            
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    "title": "PANGAEA (Biosphere)",
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    "title": "PANGAEA (Ecology)",
            
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    "type": "organization"
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    "type": "organization"
            
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  },
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  },
            
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  "owner_org": "3226ef9c-20d1-43fd-ba8f-fa35c8c9fb5d",
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  "owner_org": "c2816fc6-b5ce-42c9-b5a4-11709b658b82",
            
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  "private": false,
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  "private": false,
            
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  "publication_year": "2012",
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  "publication_year": "2012",
            
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  "related_identifiers": [
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  "related_identifiers": [
            
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    {
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    {
            
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      "authors": "Dineshram R,Wong Kevin K W,Shu Xiao,Yu Ziniu,Qian 
98
      "authors": "Dineshram R,Wong Kevin K W,Shu Xiao,Yu Ziniu,Qian 
            
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Pei Yuan,Thiyagarajan Vengatesen",
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Pei Yuan,Thiyagarajan Vengatesen",
            
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      "email_authors": ",,,,,rajan@hku.hk",
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      "email_authors": ",,,,,rajan@hku.hk",
            
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      "identifier": "https://doi.org/10.1016/j.marpolbul.2012.07.043",
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      "identifier": "https://doi.org/10.1016/j.marpolbul.2012.07.043",
            
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      "identifier_type": "DOI",
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      "identifier_type": "DOI",
            
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      "orcid_authors": ",,,,0000-0003-4074-9078,0000-0002-2062-4799",
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      "orcid_authors": ",,,,0000-0003-4074-9078,0000-0002-2062-4799",
            
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      "relation_type": "IsSupplementTo",
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      "relation_type": "IsSupplementTo",
            
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      "source": "Marine Pollution Bulletin",
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      "source": "Marine Pollution Bulletin",
            
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      "title": "Analysis of Pacific oyster larval proteome and its 
106
      "title": "Analysis of Pacific oyster larval proteome and its 
            
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response to high-CO2",
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response to high-CO2",
            
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      "year": "2012"
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      "year": "2012"
            
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    },
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    },
            
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    {
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    {
            
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      "authors": "Lavigne H\u00e9lo\u00efse,Gattuso Jean-Pierre",
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      "authors": "Lavigne H\u00e9lo\u00efse,Gattuso Jean-Pierre",
            
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      "email_authors": 
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      "email_authors": 
            
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"hlavigne@naturalsciences.be,jean-pierre.gattuso@imev-mer.fr",
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"hlavigne@naturalsciences.be,jean-pierre.gattuso@imev-mer.fr",
            
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      "identifier": "https://cran.r-project.org/package=seacarb",
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      "identifier": "https://cran.r-project.org/package=seacarb",
            
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      "identifier_type": "DOI",
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      "identifier_type": "DOI",
            
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      "orcid_authors": ",0000-0002-4533-4114",
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      "orcid_authors": ",0000-0002-4533-4114",
            
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      "relation_type": "References",
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      "relation_type": "References",
            
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      "source": "",
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      "source": "",
            
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      "title": "seacarb: seawater carbonate chemistry with R. R 
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      "title": "seacarb: seawater carbonate chemistry with R. R 
            
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package version 2.4",
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package version 2.4",
            
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      "year": "2011"
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      "year": "2011"
            
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    }
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    }
            
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  ],
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  ],
            
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  "relationships_as_object": [],
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  "relationships_as_object": [],
            
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  "relationships_as_subject": [],
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  "relationships_as_subject": [],
            
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  "repository_name": "PANGAEA (Data Publisher for Earth & 
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  "repository_name": "PANGAEA (Data Publisher for Earth & 
            
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Environmental Science)",
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Environmental Science)",
            
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  "resource_type": "text/tab-separated-values - filename: 
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  "resource_type": "text/tab-separated-values - filename: 
            
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Dineshram_2012",
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Dineshram_2012",
            
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  "resources": [],
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  "resources": [],
            
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  "source_metadata_created": "2012",
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  "source_metadata_created": "2012",
            
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  "source_metadata_modified": "",
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  "source_metadata_modified": "",
            
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  "state": "active",
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  "state": "active",
            
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  "subject_areas": [
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  "subject_areas": [
            
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    {
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    {
            
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      "subject_area_additional": "",
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      "subject_area_additional": "",
            
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      "subject_area_name": "BiologicalClassification"
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      "subject_area_name": "BiologicalClassification"
            
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    },
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    },
            
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    {
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    {
            
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      "subject_area_additional": "",
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      "subject_area_additional": "",
            
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      "subject_area_name": "Biosphere"
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      "subject_area_name": "Biosphere"
            
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    },
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    },
            
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    {
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    {
            
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      "subject_area_additional": "",
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      "subject_area_additional": "",
            
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      "subject_area_name": "Chemistry"
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      "subject_area_name": "Chemistry"
            
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    },
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    },
            
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    {
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    {
            
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      "subject_area_additional": "",
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      "subject_area_additional": "",
            
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      "subject_area_name": "Ecology"
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      "subject_area_name": "Ecology"
            
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    },
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    },
            
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    {
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    {
            
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      "subject_area_additional": "",
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      "subject_area_additional": "",
            
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      "subject_area_name": "Oceans"
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      "subject_area_name": "Oceans"
            
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    }
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    }
            
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  ],
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  ],
            
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  "tags": [
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  "tags": [
            
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    {
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    {
            
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      "display_name": "1000 L or  1 m2",
            
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      "id": "d920ecdb-c44e-43f2-bb4c-ffdc3a3c398c",
            
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      "name": "1000 L or  1 m2",
            
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      "display_name": "Animalia",
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      "display_name": "Animalia",
            
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      "id": "e645e194-a2f7-40f1-ae7c-c1496be6f6bf",
            
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      "name": "Animalia",
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      "name": "Animalia",
            
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      "state": "active",
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      "state": "active",
            
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      "vocabulary_id": null
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      "vocabulary_id": null
            
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      "display_name": "Coast and continental shelf",
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      "display_name": "Coast and continental shelf",
            
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      "id": "58eb1929-34b5-4fd9-ac44-824f0e51de40",
            
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      "name": "Coast and continental shelf",
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      "name": "Coast and continental shelf",
            
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      "state": "active",
            
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    {
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    {
            
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      "display_name": "Containers and aquaria 20-1000 L or  1 m2",
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      "display_name": "Containers and aquaria 20",
            
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      "id": "a9d9036d-3fe8-4fb1-bcb9-07b8a3a3fe11",
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      "id": "18d57eca-7aec-4d8a-9a57-92bf32a45d53",
            
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      "name": "Containers and aquaria 20-1000 L or  1 m2",
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      "name": "Containers and aquaria 20",
            
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      "state": "active",
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      "state": "active",
            
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    },
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    },
            
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    {
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    {
            
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      "display_name": "Crassostrea gigas",
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      "display_name": "Crassostrea gigas",
            
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      "id": "44a90705-8dc8-41ad-a3c4-d60cdbce94bf",
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      "id": "44a90705-8dc8-41ad-a3c4-d60cdbce94bf",
            
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      "name": "Crassostrea gigas",
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      "name": "Crassostrea gigas",
            
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      "state": "active",
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      "state": "active",
            
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      "vocabulary_id": null
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      "vocabulary_id": null
            
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    },
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    },
            
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    {
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    {
            
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      "display_name": "Gene expression incl. proteomics",
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      "display_name": "Gene expression incl. proteomics",
            
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      "id": "a266e76f-1f2a-427a-97e6-8e248d591f17",
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      "id": "a266e76f-1f2a-427a-97e6-8e248d591f17",
            
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      "name": "Gene expression incl. proteomics",
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      "name": "Gene expression incl. proteomics",
            
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      "state": "active",
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      "state": "active",
            
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      "vocabulary_id": null
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      "vocabulary_id": null
            
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    },
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    },
            
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    {
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    {
            
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      "display_name": "Growth-Morphology",
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      "display_name": "Growth",
            
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      "id": "b00c4eac-980d-42b2-bae9-0aa1b212cf54",
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      "id": "898cbb0c-ff61-4ca3-9e35-0ef6fbb8eb98",
            
195
      "name": "Growth-Morphology",
202
      "name": "Growth",
            
196
      "state": "active",
203
      "state": "active",
            
197
      "vocabulary_id": null
204
      "vocabulary_id": null
            
198
    },
205
    },
            
199
    {
206
    {
            
200
      "display_name": "Laboratory experiment",
207
      "display_name": "Laboratory experiment",
            
201
      "id": "c6c00754-c769-4932-a517-bff2c9512884",
208
      "id": "c6c00754-c769-4932-a517-bff2c9512884",
            
202
      "name": "Laboratory experiment",
209
      "name": "Laboratory experiment",
            
203
      "state": "active",
210
      "state": "active",
            
204
      "vocabulary_id": null
211
      "vocabulary_id": null
            
205
    },
212
    },
            
206
    {
213
    {
            
207
      "display_name": "Mollusca",
214
      "display_name": "Mollusca",
            
208
      "id": "006d5f6d-11b3-4c34-a35a-879d7cd074c8",
215
      "id": "006d5f6d-11b3-4c34-a35a-879d7cd074c8",
            
209
      "name": "Mollusca",
216
      "name": "Mollusca",
            
t
t
217
      "state": "active",
            
218
      "vocabulary_id": null
            
219
    },
            
220
    {
            
221
      "display_name": "Morphology",
            
222
      "id": "2345107d-a1a2-43c1-8b38-d670ea499006",
            
223
      "name": "Morphology",
            
210
      "state": "active",
224
      "state": "active",
            
211
      "vocabulary_id": null
225
      "vocabulary_id": null
            
212
    },
226
    },
            
213
    {
227
    {
            
214
      "display_name": "North Pacific",
228
      "display_name": "North Pacific",
            
215
      "id": "efbdbaff-aa72-4a57-8e03-e9f84253d644",
229
      "id": "efbdbaff-aa72-4a57-8e03-e9f84253d644",
            
216
      "name": "North Pacific",
230
      "name": "North Pacific",
            
217
      "state": "active",
231
      "state": "active",
            
218
      "vocabulary_id": null
232
      "vocabulary_id": null
            
219
    },
233
    },
            
220
    {
234
    {
            
221
      "display_name": "Pelagos",
235
      "display_name": "Pelagos",
            
222
      "id": "012f5b69-4e75-4f54-8ac4-8bf192cafaa2",
236
      "id": "012f5b69-4e75-4f54-8ac4-8bf192cafaa2",
            
223
      "name": "Pelagos",
237
      "name": "Pelagos",
            
224
      "state": "active",
238
      "state": "active",
            
225
      "vocabulary_id": null
239
      "vocabulary_id": null
            
226
    },
240
    },
            
227
    {
241
    {
            
228
      "display_name": "Single species",
242
      "display_name": "Single species",
            
229
      "id": "88de69be-3bdd-4cf8-b6a1-386d72c5888d",
243
      "id": "88de69be-3bdd-4cf8-b6a1-386d72c5888d",
            
230
      "name": "Single species",
244
      "name": "Single species",
            
231
      "state": "active",
245
      "state": "active",
            
232
      "vocabulary_id": null
246
      "vocabulary_id": null
            
233
    },
247
    },
            
234
    {
248
    {
            
235
      "display_name": "Tropical",
249
      "display_name": "Tropical",
            
236
      "id": "db8bd80f-8578-455b-acc6-6adbeae406b8",
250
      "id": "db8bd80f-8578-455b-acc6-6adbeae406b8",
            
237
      "name": "Tropical",
251
      "name": "Tropical",
            
238
      "state": "active",
252
      "state": "active",
            
239
      "vocabulary_id": null
253
      "vocabulary_id": null
            
240
    },
254
    },
            
241
    {
255
    {
            
242
      "display_name": "Zooplankton",
256
      "display_name": "Zooplankton",
            
243
      "id": "9a829b96-807f-48c1-84c6-8fa50a64f5a5",
257
      "id": "9a829b96-807f-48c1-84c6-8fa50a64f5a5",
            
244
      "name": "Zooplankton",
258
      "name": "Zooplankton",
            
245
      "state": "active",
259
      "state": "active",
            
246
      "vocabulary_id": null
260
      "vocabulary_id": null
            
247
    }
261
    }
            
248
  ],
262
  ],
            
249
  "title": "Analysis of Pacific oyster larval proteome and its 
263
  "title": "Analysis of Pacific oyster larval proteome and its 
            
250
response to high-CO2",
264
response to high-CO2",
            
251
  "type": "vdataset",
265
  "type": "vdataset",
            
252
  "url": "https://doi.org/10.1594/PANGAEA.823757"
266
  "url": "https://doi.org/10.1594/PANGAEA.823757"
            
253
}
267
}