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CHO stress induced product production

Carbondioxide feed and macronutrient supply were investigated regarding their effects on cell growth, cell size and cell-specific productivity. Our research reveals a stress related increase in mAb production for carbondioxide limitation, glucose overfeeding and increased glutamate supply as well as the importance of glutamine for proliferation. Together with the discovery of a non-linear correlation between cell enlargement an increased specific productivity, this marks the first step towards better process understanding and optimization.

Data and Resources

Cite this as

Dörte Solle, Jana Schellenberg (2021). Dataset: CHO stress induced product production. https://doi.org/10.25835/0066265

DOI retrieved: May 26, 2021

Additional Info

Field Value
Imported on October 14, 2021
Last update January 12, 2023
License CC0-1.0
Source https://data.uni-hannover.de/dataset/cho-stress-induced-product-production
Author Dörte Solle, Jana Schellenberg
Author Email Dörte Solle, Jana Schellenberg
Maintainer Dörte Solle
Maintainer Email Dörte Solle
Source Creation 26 May, 2021, 07:37 AM (UTC+0000)
Source Modified 20 January, 2022, 13:48 PM (UTC+0000)