In silico electrocardiograms of 1.8 million ventricular extrasystoles and corresponding activation maps (part 1)

doi:doi:10.35097/1425

In silico electrocardiograms of 1.8 million ventricular extrasystoles and corresponding activation maps (part 1)

Abstract: 1.8 million ECGs derived from multiscale simulations of cardiac electrophysiology of ventricular extrasystoles. 1000 anatomical variants of a bi-ventricular mesh x 600 excitation origins x 3 heart positions in the torso. TechnicalRemarks: This dataset contains about 1.8 million body surface potentials (BSPs) simulated using 1000 heart models generated using a statistical shape model. It has been used in [1,1a]. Here, only the noise-free BSPs are provided.

Due to its size, this is a multi-part dataset. Part 1: https://doi.org/10.5445/IR/1000156139 Part 2: https://doi.org/10.5445/IR/1000156554 Part 3: https://doi.org/10.5445/IR/1000156555 Part 4: https://doi.org/10.5445/IR/1000156556 Part 5: https://doi.org/10.5445/IR/1000156557

Each archive XXXX-YYYY.tar contains 20 heart models and corresponding signals. Each subdirectory within the archive contains:

heart.vtp: A triangle mesh of the heart including the point data:
ab, rt, rtCos, rtSin, tm, tv: Consistent biventricular coordinates [2].
class: Boundary regions used as input for the computation of fiber orientations [3].
trigger: 1-based indices of the ca. 600 foci (-1000 if not a focus).
heart_transform_matrices.mat: A 1 x 3 cell array containing 4 x 4 transformation matrices that describe the pose of the heart within the torso. Apply the matrix from heart_transform_matrices.mat to the nodes in heart.vtp.
actTimes.mat: A numNodes x numFoci matrix of activation times computed using the fast iterative method [4,5] (conduction velocity in fiber direction: 1 m/s, perpendicular to fiber direction: 1/2.7 m/s).
bsp.mat:
bsp: A numElectrodes x numTimeSamples x numHeartPoses x numFoci matrix of BSPs computed by aligning a transmembrane voltage template with scaled activation times (see actTimeScalings.mat below) and solving the second bidomain equation using the boundary element method [6].
bspEnd: Time index of the end of depolarization (largest scaled activation time).

The archive general.tar contains heart-model-independent data and parameters used to generate the individual heart models:

torso.vtp: A triangle mesh of the torso including the point data:
electrodes: 1-based indices of the 200 electrodes (-1000 if not an electrode).
heart_meanshape.vtp: A triangle mesh of the mean shape of the statistical shape model [7,8].
heart_shapemodel.mat:
pc: A 3*numNodes x numModes matrix of principal components (numModes = 100).
var: A numModes x 1 vector of variances.
weights: A numModes x numModels matrix of weights used to generate the 1000 heart models.
heart_alignment_matrix.mat: A 4 x 4 transformation matrix describing the alignment of the mean shape with the torso-specific heart. Only to be appleid to node coordinates in within general.tar (already contained in heart_transform_matrices.mat).
heart_transform_params.mat: A struct containing roll, pitch, yaw angles and x, y, z translations used to generate the heart_transform_matrices.mat (see above).
fiber_angles.mat:
alphaEndo: numModels x 1 vector of endocardial fiber angles used to generate fiber orientations.
alphaEpi: numModels x 1 vector of epicardial fiber angles used to generate fiber orientations.
actTimeScalings.mat:
A numModels x numFoci matrix of factors used to scale the activation times.
tmv_template.mat: The transmembrane voltage time course used to compute BSPs.
heart_classes.vtp: A coarse triangle mesh of the mean shape used for fuzzy classification.
heart_classes_subdiv.vtp: A subdivided version of the coarse triangle mesh of the mean shape used to convert between Cobiveco and barycentric coordinates.

[1] https://doi.org/10.48550/arXiv.2209.08095 [1a]https://doi.org/10.1016/j.artmed.2023.102619 [2] https://doi.org/10.1016/j.media.2021.102247 [3] https://github.com/KIT-IBT/LDRB_Fibers [4] https://github.com/KIT-IBT/FIM_Eikonal [5] https://doi.org/10.1137/120881956 [6] https://doi.org/10.1016/j.cmpb.2007.09.004 [7] https://doi.org/10.5281/zenodo.4506463 [8] https://doi.org/10.1016/j.media.2015.08.009

BibTex:

@dataset{Pilia_Nicolas_and_Schuler_Steffen_and_Rees_Maike_and_Moik_Gerald_and_Potyagaylo_Danila_and_Dössel_Olaf_and_Loewe_Axel_2023,
    abstract = {Abstract: 1.8 million ECGs derived from multiscale simulations of cardiac electrophysiology of ventricular extrasystoles. 1000 anatomical variants of a bi-ventricular mesh x 600 excitation origins x 3 heart positions in the torso.
TechnicalRemarks: This dataset contains about 1.8 million body surface potentials (BSPs) simulated using 1000 heart models generated using a statistical shape model.
It has been used in [1,1a]. Here, only the noise-free BSPs are provided.

Due to its size, this is a multi-part dataset.
Part 1: https://doi.org/10.5445/IR/1000156139
Part 2: https://doi.org/10.5445/IR/1000156554
Part 3: https://doi.org/10.5445/IR/1000156555
Part 4: https://doi.org/10.5445/IR/1000156556
Part 5: https://doi.org/10.5445/IR/1000156557

Each archive XXXX-YYYY.tar contains 20 heart models and corresponding signals. Each subdirectory within the archive contains:

- heart.vtp:
  A triangle mesh of the heart including the point data:
  - ab, rt, rtCos, rtSin, tm, tv: Consistent biventricular coordinates [2].
  - class: Boundary regions used as input for the computation of fiber orientations [3].
  - trigger: 1-based indices of the ca. 600 foci (-1000 if not a focus).

- heart_transform_matrices.mat:
  A 1 x 3 cell array containing 4 x 4 transformation matrices that
  describe the pose of the heart within the torso.
  Apply the matrix from heart_transform_matrices.mat to the nodes in heart.vtp.

- actTimes.mat:
  A numNodes x numFoci matrix of activation times computed using the fast iterative method [4,5]
  (conduction velocity in fiber direction: 1 m/s, perpendicular to fiber direction: 1/2.7 m/s).

- bsp.mat:
  - bsp: A numElectrodes x numTimeSamples x numHeartPoses x numFoci matrix of BSPs computed by aligning a transmembrane voltage template with
         scaled activation times (see actTimeScalings.mat below) and solving the second bidomain equation using the boundary element method [6].
  - bspEnd: Time index of the end of depolarization (largest scaled activation time).

The archive general.tar contains heart-model-independent data and parameters used to generate the individual heart models:

- torso.vtp:
  A triangle mesh of the torso including the point data:
  - electrodes: 1-based indices of the 200 electrodes (-1000 if not an electrode).

- heart_meanshape.vtp:
  A triangle mesh of the mean shape of the statistical shape model [7,8].

- heart_shapemodel.mat:
  - pc: A 3*numNodes x numModes matrix of principal components (numModes = 100).
  - var: A numModes x 1 vector of variances.
  - weights: A numModes x numModels matrix of weights used to generate the 1000 heart models.

- heart_alignment_matrix.mat:
  A 4 x 4 transformation matrix describing the alignment of the mean shape with the torso-specific heart. Only to be appleid to node coordinates in within general.tar (already contained in heart_transform_matrices.mat).

- heart_transform_params.mat:
  A struct containing roll, pitch, yaw angles and x, y, z translations used to generate the heart_transform_matrices.mat (see above).

- fiber_angles.mat:
  - alphaEndo: numModels x 1 vector of endocardial fiber angles used to generate fiber orientations.
  - alphaEpi: numModels x 1 vector of epicardial fiber angles used to generate fiber orientations.

- actTimeScalings.mat:
  - A numModels x numFoci matrix of factors used to scale the activation times.

- tmv_template.mat:
  The transmembrane voltage time course used to compute BSPs.

- heart_classes.vtp:
  A coarse triangle mesh of the mean shape used for fuzzy classification.

- heart_classes_subdiv.vtp:
  A subdivided version of the coarse triangle mesh of the mean shape used to convert between Cobiveco and barycentric coordinates.

[1] https://doi.org/10.48550/arXiv.2209.08095
[1a]https://doi.org/10.1016/j.artmed.2023.102619
[2] https://doi.org/10.1016/j.media.2021.102247
[3] https://github.com/KIT-IBT/LDRB_Fibers
[4] https://github.com/KIT-IBT/FIM_Eikonal
[5] https://doi.org/10.1137/120881956
[6] https://doi.org/10.1016/j.cmpb.2007.09.004
[7] https://doi.org/10.5281/zenodo.4506463
[8] https://doi.org/10.1016/j.media.2015.08.009},
    author = {Pilia, Nicolas and Schuler, Steffen and Rees, Maike and Moik, Gerald and Potyagaylo, Danila and Dössel, Olaf and Loewe, Axel},
    doi = {10.35097/1425},
    institution = {RADAR},
    keyword = {'ECG', 'extrasystoles', 'in silico'},
    title = {In silico electrocardiograms of 1.8 million ventricular extrasystoles and corresponding activation maps (part 1)},
    url = {https://service.tib.eu/ldmservice/vdataset/rdr-doi-10-35097-1425},
    year = {2023}
}